Efficient harvest from the bioreactor is essential to any successful cell culture process but is often labor intensive as laboratory personnel closely monitor and adjust filtration process parameters. Experienced bioprocessors know that investment in automation of the harvest process yields higher quality, enhanced safety, and better efficiency, giving them an edge over competitors.
Scilog is focused on improving the quality and efficiency of customers’ processes in the biopharmaceutical industry through enhancements and automation of sensing, filtration and other processing needs. The company’s HarvestClear filtration system is a combination of Scilog’s fluid handling technology and pressure sensing with a single use filtration manifold optimized to clarify high cell density bioreactor outputs. Three sizes are available to accommodate bioreactor outputs from 1L to 20L. The fluid handling system is based on an automated laboratory scale NFF system with electronic HMI and specialized software. The system’s pre-installed software allows user selectable limits and alarms for safe, consistent process performance without constant operator attendance. The system responds to sensor feedback to maintain user-defined filter back pressure or filtrate flow rates. A disposable pressure sensors and optional integrated electronic scale are included as well as a programmable peristaltic pump allowing completely unattended NFF processing of bioreactor outputs to user specified parameters. Filter manifolds are provided in a gamma-irradiated sterile and pre-flushed state ready for use. Once the user defined parameters are entered, the system can run unattended freeing personnel to focus on other tasks.
Scilog provides sensor technology and automated lab-scale and production systems for the biopharmaceutical industry
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Parker Scilog HarvestClear Datasheet.pdf |
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0.21 MB |