Pharmaceutical granulators

Pharmaceutical granulators are often used with active substance mixtures to be processed into granulates, a process also known as compaction.

Dry granulation of pharmaceutical powders

With the Pharmapaktor® Serie (Pharmapaktors series L, K and C 250) from Hosokawa Alpine, active substance mixtures are processed into granulate.

For this the powder is first pressed into flakes/pellets. These are often crushed with a Flake Crusher into granulate.

Compaction (dry granulation) is understood to be the compression of powder between two synchronized, counter rotating rollers. The powder is fed to the counter rotating rollers in a regulated manner. Here, adhesive forces between the product particles are created under high pressure between the rollers.

For capsule or sachet filling the granulate must be de-dusted in a screening machine. The sieved fines can then be directly fed to the Pharmapaktor again

Hosokawa Alpine (www.hosokawa-alpine.com) offers comminution technology for the production of powders, particles and bulk materials: from mills and classifiers to complete turnkey systems. For R&D and laboratory applications, as well as for industrial production. Tailor-made solutions for powder and particle processing in the chemicals industry, for paints and pigments, mineral raw materials and metals, pharmaceutics and cosmetics, foodstuffs and animal feed, and for industrial recycling.